Focus on understanding the etiology and treatment for youth with, and at-risk for, mood disorders and suicide. Her work aims to develop improved prevention and intervention strategies for this population informed by an enhanced understanding of the relationship between biological and psychosocial determinants of mood disorder and suicide.

Representative Publications

Goldstein TR, Franzen PL. Sleep difficulties and suicidality in youth: current research and future directions. Curr Opin Psychol. 2020 Aug;34:27-31. PMID: 31539832

Hafeman DM, Ostroff AN, Feldman J, Hickey MB, Phillips ML, Creswell D, Birmaher B, Goldstein TR. Mindfulness-based intervention to decrease mood lability in at-risk youth: Preliminary evidence for changes in resting state functional connectivity. J Affect Disord. 2020 Jul 14;276:23-29. PMID: 32697703

Goldstein TR, Krantz ML, Fersch-Podrat RK, Hotkowski NJ, Merranko J, Sobel L, Axelson D, Birmaher B, Douaihy A. A brief motivational intervention for enhancing medication adherence for adolescents with bipolar disorder: A pilot randomized trial. J Affect Disord. 2020 Mar 15;265:1-9. PMID: 31957686    

Sewall C, Goldstein TR, Salk, R, Merranko J, Gill MK, Strober M, Keller M, Hafeman D, Ryan ND, Yen S, Hower H, Liao F, Birmaher B. Interpersonal relationships and suicidal ideation in youth with bipolar disorder. Arch Suic Res. 2019 Jul  3;1-15. PMID: 31159677

Casement MD, Goldstein TR, Merranko J, Gratzmiller SM, Franzen PL. Sleep and parasympathetic activity during rest and stress in healthy adolescents and adolescents with bipolar disorder. Psychosom Med. 2019 Jul 81;9:782-790. PMID: 31369483.

Goldstein TR, Merranko J, Krantz M, Garcia M, Franzen P, Levenson J, Axelson D, Birmaher B, Frank E. Early intervention for adolescents at-risk for bipolar disorder: A pilot randomized trial of Interpersonal and Social Rhythm Therapy. J Affect Disord. 2018 Aug:235;348-356. PMID: 29665518

Birmaher B, Merranko JA, Goldstein TR, Gill MK, Goldstein BI, Hower H, Yen S, Hafeman D, Strober M, Diler RS, Axelson DA< Ryan ND, Keller MB. A risk calculator to predict the individual risk of conversion from subthreshold bipolar symptoms to bipolar disorder I or II in youth. J Am Acad Child Adolesc Psychiatry. 2018 Oct:57(10);755-763. PMID: 30274650

Kennard B, Goldstein TR, Foxwell A, McMakin D, Wolfe K, Biernesser C, Moorehead A, Douaihy A, Zullo L, Wentroble E, Owen V, Zelazny J, Iyengar S, Porta G, Brent DA. As safe as possible (ASAP): A brief app-supported inpatient intervention to prevent post-discharge suicidal behavior in hospitalized, suicidal adolescents. Am J Psychiatry. 2018 Sep 1;175(9):864-872. PMID: 30021457

Victor SE, Scott LN, Stepp SD, Goldstein TR. I want you to want me: Interpersonal stress and affective experiences as within-person predictors of nonsuicidal self-injury and suicide urges in daily life. Suicide and Life Threatening Behavior. 2018 Aug 29. PMID: 30159910

Hafeman D, Merranko J, Goldstein TR, Axelson D, Goldstein B, Monk K, Hickey MB, Sakolsky D, Diler R, Iyengar S, Brent D, Kupfer D, Kattan MW, Birmaher B. Assessment of a person-level risk calculator to predict new-onset bipolar spectrum disorder in youth at familial risk. JAMA Psychiatry. 2017 Aug:74(8);841-847. PMID: 28678992

Levenson JC, Soehner AM, Rooks BT, Goldstein TR, Diler R, Merranko R, Axelson D, Goldstein BI, Brent DA, Hafeman D, Hickey MB, Monk, K, Sakolsky D, Kupfer DJ, Birmaher B. Longitudinal sleep phenotypes among offspring of bipolar parents and community controls. J Affect Disord. 2017 Mar;215. PMID: 28315578.

Goldstein TR, Krantz M, Merranko J, Garcia M, Sobel L, Rodriguez C, Douaihy A, Axelson DA, Birmaher B. Medication adherence among adolescents with bipolar disorder. J Child Adol Psychopharmacol. 2016 Dec;26(10). PMID: 27419273

Goldstein TR, Fersch RK, Rivera M, Axelson DA, Merranko J, Yu H, , Brent DA, Birmaher B. Dialectical Behavior Therapy (DBT) for Adolescents with Bipolar Disorder: Results from a Pilot Randomized Trial. J Child Adol Psychopharmacol. 2015 Mar;25(2):140-149. PMID: 25010702

Schaffer A, Isometsa E, Tondo L, Moreno D, Turecki G, Reis C, Cassidy F, Sinyor M, Azorin J, Kessing L, Ha K, Goldstein TR, Weizman A, Beutrais A, Chou Y, Diazgranados N, Levitt A, Phillips M, Zarate C, Rihmer Z, Yatham L. International Society for Bipolar Disorders task force on suicide: Meta-analyses and meta-regression of correlates of suicide attempts and suicide deaths in bipolar disorder. Bipolar Disord. 2015 Feb;17(1):1-16. PMID: 25329791

Goldstein TR, Ha W, Axelson DA, Goldstein BI, Liao F, Gill MK, Ryan ND, Yen S, Hunt J, Hower H, Keller M, Strober M, Birmaher B. Predictors of prospectively observed suicide attempts among youth with bipolar disorder. Arch Gen Psychiatry. 2012 Nov;69(11):1113-1122.  PMID: 22752079