4119 Sennott Square 210 S. Bouquet St.
Pittsburgh, PA 15260
Accepting Graduate Students: Yes
Addictive Behaviors Research Laboratory
Our laboratory uses both animal and human models to examine nicotine/tobacco dependence. Important features of our laboratory are an emphasis on drug-seeking and drug-taking behavior, the translation of information between animal and human research, and the use of multiple levels of analysis (e.g., behavioral, developmental, neurobiological, pharmacological). Our current research addresses the public health consequences of smoking and potential regulation of tobacco products by the FDA to reduce the harm caused by cigarettes. In the animal laboratory, we use a rodent model of nicotine self-administration that allows us to study the factors that promote/retard nicotine-taking behavior, the behavioral and neurobiological mechanisms underlying nicotine reinforcement, and the influence of other tobacco constituents. In the human laboratory, we examine the potential impact of reduction of nicotine in cigarettes on smoking behavior, mood, cognition, toxicant exposure, tobacco dependence and subjective experience.
Principal Investigator: Eric C. Donny, PhD
Location: 211 LSA (animal lab) & 4129 Sennott Square (human lab)
Eric Donny (PI): firstname.lastname@example.org
- PhD, University of Pittsburgh
- National Academy of Sciences, Kavli Frontiers of Science Fellow
- Society for Research on Nicotine and Tobacco New Investigator Award (2003)
- Robert Wood Johnson Faculty Scholar (2002-present)
- College on Problems of Drug Dependence Early Career Investigator Award (2002)
- Andrew Mellon Predoctoral Fellowship (1997)
- Weisberg-Colavita Award for Excellence in Biopsychology (1996)
Donny, E.C., Denlinger, R.L., Tidey, J.W., Koopmeiners, J.S., Benowitz, N.L., Vandrey, R.G., al’Absi, M., Carmella, S.G., Cinciripini, P.M., Dermody, S.S., Drobes, D.J., Hecht, S.S., Jensen, J., Lane, T., Le, C.T., McClernon, F.J., Montoya, I.D., Murphy, S.E., Robinson, J.D., Stitzer, M.L., Strasser, A.A., Tindle, H., Hatsukami, D.K. (2015). Randomized trial of reduced-nicotine standards for cigarettes. New England Journal of Medicine 373(14):1340-9. (Designated “Special Article” with accompanying editorial).
Dermody, S.S.*, Tidey, J.W., Denlinger, R.L., Pacek, L.R., al'Absi, M., Drobes, D.J., Hatsukami, D.K., Vandrey, R., Donny, E.C. (2016). The Impact of Smoking Very Low Nicotine Content Cigarettes on Alcohol Use. Alcohol Clin Exp Res. 40(3):606-15. *first author was mentee.
Smith, T.T.*, Rupprecht, L.E., Cwalina, S., Ominus, M., Murphy, S., Donny, E.C., Sved, A.F. (in press). Effects of monoamine oxidase inhibition on the reinforcing properties of low-dose nicotine. Neuropsychopharmacology. *first author was mentee.
Smith, T.T.*, Sved, A.F., Hatsukami, D.K., Donny, E.C. (2014). Nicotine reduction as an increase in the unit price of cigarettes: A behavioral economics approach. Preventive Medicine 68:23-8. *first author was mentee.
Donny, E.C., Hatsukami, D.K., Benowitz, N.L., Sved, A.F., Tidey, J.W., Cassidy, R.N. (2014). Reduced nicotine product standards for combustible tobacco: Building an empirical basis for effective regulation. Preventive Medicine 68:17-22.